目录
一、前言··························································2
二、乌头碱毒性研究················································2
三、川乌的抗肿瘤作用··············································3
（一）抗肿瘤实验研究··············································3
1、调节基因表达····················································4
2、诱导肿瘤细胞凋亡··············································4
3、诱导细胞分化··················································4
4、抑制肿瘤生产··················································4（二）抗肿瘤临床作用·················································5
1、治疗胃癌······················································5
2、治疗肝癌······················································5
3、治疗食管癌····················································5
4、治疗骨癌······················································5四、总结与展望····················································5
五、参考文献··················································6
前言
川乌，正名为乌头（学名：Aconitum carmichaelii / Radix ），别名：鹅儿花、铁花、五毒；被子植物门，毛莨科，乌头属。英文名Aconite Root， 生于山地草坡或灌丛中。栽培于平地肥沃的砂质土壤，主要栽培于四川。分布于长江中下游，北至秦岭和山东东部，南至广西北部。川乌是毛莨科植物川乌的干燥块根，化学成分是双脂型二萜类生物碱，约0.4%~0.8%，包括乌头碱（Aconitine）,次乌头碱（Hypaconitine），杰斯乌头碱（Jasaconitine），异翠雀乌头碱
